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gamma-Hydroxybutyric acid or γ-Hydroxybutyric acid (GHB), generally known as four-hydroxybutanoic acid, is often a naturally developing neurotransmitter in addition to a psychoactive drug. It is just a precursor to GABA, glutamate, and glycine in specified brain parts. It acts over the GHB receptor and is also a weak agonist in the GABAB receptor. GHB has long been use while in the healthcare placing as being a normal anesthetic and as being a cure for cataplexy, narcolepsy, and alcoholism.It's also use illegally as an intoxicant, being an athletic performance enhancer, like a day rape drug, and to be a recreational drug.

It is commonly use in more info the form of a salt, for instance sodium γ-hydroxybutyrate (NaGHB, sodium oxybate, or Xyrem) or potassium γ-hydroxybutyrate (KGHB, potassium oxybate). GHB is also generate due to fermentation, and is locate in small quantities in some beers and wines, beef and little citrus fruits.

Succinic semialdehyde dehydrogenase deficiency can be a disorder that triggers GHB to build up during the blood.

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